Not including Cyberpsychosis feels like a strong choice to me, but I think I understand it for the video game.

Kinda counter to the power fantasy of the majority of the gameplay.

I'm really excited for the possible addition of something like cyberpsychosis, or at least cyberware limits with the in-world excuse for those limits being cyberpsychosis. It has the potential to make the player feel less like some kind of truly special "chosen one" who's exempt from the rules everyone else has to follow and wins because of it, and more like just another punk on the street, who makes it — or doesn't — in spite of that. It would also add a real sense of fear and worry and downsides to balance out all the chrome you can get, which might balance the game (and the power fantasy aspect) a bit more.

Hopefully the debuffs are big enough to have impact. Deux Ex: Mankind Divided had the overclock penalty for activating too many experimental augs, but the penalties were basically just annoyances, screen glitches and the like, plus there was a quest to just make overclocking not affect you negatively.. But yeah, I didn't expect full cyberpyschosis, but I did see some suggestions before, like occasionally having enemies that don't actually exist in the middle of a fight, or civilians looking hostile to bring out the NCPD against you. But we'll see, from what I'm seeing of the expansion from news/videos, it's looking great so far.