AI-powered CRISPR could lead to faster gene therapies, Stanford Medicine study finds

a year ago by DarkBluemetal to c/technology

CRISPR-GPT, a large language model developed at Stanford Medicine, is accelerating gene-editing processes and increasing accessibility to CRISPR.
Horta 18 points a year ago

"Hey...Crisper.GP...T...think...you've mixed up the genes for my ass and...elbows..."

"Oh, you're totally alright! I apologise about that. ๐Ÿ˜€"

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TribblesBestFriend 5 points a year ago

"Oh, you're totally alright! I apologise about that. ๐Ÿ˜€"

Here your ass on your elbow like you asked

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echodot 2 points a year ago

To be honest you're probably better off just making a T-Rex from the start let it eat you and just get it over with.

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Perspectivist 1 point a year ago
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Muffi 6 points a year ago

What a shame that we have created a world where this will only benefit a wealthy minority.

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Treczoks 1 point a year ago

... or to funny looking specimen. Radioactivity no longer required.

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panda_abyss 0 points a year ago

I am asking that all the people doing this watch Jurassic Park at least once.

I'll let experts do their thing, but this kind of thing worries me. I never had "there is no singularity, AI just engineers a generic disease by accident and kills is all" on my bingo.

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Telorand 5 points a year ago

This is actually an excellent use case for AI. Physics and chemistry as scientific disciplines are lots of complex pattern recognition and manipulation. AI is just a pattern recognition and generation engine, despite what the tech bros and apologists like to tell us.

What these engines generate will ultimately be vetted by experts before it even goes to trials. Scientists don't just take things on blind faith simply because a robot or even another expert comes up with something; their entire deal is to understand their particular field of study in great detail, after all!

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Cybersteel 6 points a year ago

Back in the day, I used to fold proteins at home.

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echodot 1 point a year ago

There's something similar that you can do with categorising stars. Basically they want to map as much of the universe as we can see. We've got the photos the problem is is that when you zoom in on a 1 mm by 1 mm patch of sky 1,100,000 new stars appear. It's going to take a while, even with AI.

You never know you might find a Dyson sphere one day.

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Telorand 1 point a year ago

Same

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echodot 4 points a year ago

Of course the actual moral of Jurassic Park is have a well staffed IT team and not just one random guy who you under pay.

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Reverendender 3 points a year ago

Eh. Read the book first.

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webghost0101 0 points a year ago

Machine learning sure, but an llm? For anything other then as a module to translate abstract data into words that just seem weird

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echodot 5 points a year ago

Well I'm sure you know more than the scientists at Stanford university.

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webghost0101 1 point a year ago

I am not saying i understand it at all. My comment is genuine, not rhetorical.

On the contrary i express that i do not understand this to the point of deeming it strange or weird, triggering my curiosity.

I was hoping someone would chime in an explain how text generator techniques (which i do know alot about) known to have no capacity to use real world reason or logic can be used to help solve dna puzzles unless as a sub module of general machine learning. In which that later case would be within my understanding

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muusemuuse -1 points a year ago

This seems irresponsible.

There was an old game from the PlayStation days called Xenogears. There was a population of mutants and monsters in it than came about from fucking with DNA irresponsibly. Iโ€™m reminded of that obnoxious rat-man from the Kislev prison.

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9488fcea02a9 -2 points a year ago

Lol... people downvoting stanford university

Lemmy is a wild place.... left wing maga, i guess

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rapchee 6 points a year ago

it's useless hype, "ai could do x one day" is speculation at best

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Perspectivist 6 points a year ago

DeepMindโ€™s AlphaFold solved the decades-old protein folding problem, and its results are already being used in drug and vaccine development.

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rapchee 0 points a year ago

is this what the article talks about?

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Perspectivist 4 points a year ago

CRISPR is the tool that lets us precisely edit genes in DNA, which contain the instructions for making proteins. AlphaFold is the AI tool that helped us understand what those edits actually do. Itโ€™s the 3D shape of the protein that determines its function - without understanding protein folding, gene editing would be like changing code in a language you donโ€™t fully understand and just hoping it works.

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Perspectivist 3 points a year ago

It says AI in the title. That's all information they need. Most people on social media don't think - they react.

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echodot 0 points a year ago

No I doesn't.

The problem is the term AI has become so broadly used that it's become meaningless. There is a popular quote about how the quota doesn't want AI to replace artistic jobs, as if it will. As if generative AI and large language models and projects like this are the same.

When the bubble bursts, (please let it be soon) we're still going to have all of the science AIs because those are actually useful. What we don't need is AI girlfriends.

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Perspectivist 3 points a year ago

AI-powered

Yes it does.

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echodot 0 points a year ago

Yes I know the title has the word AI powered in it. I never claimed otherwise.

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