This one made me think

8 months ago by The Picard Maneuver to c/memes

The meme is talking about a common probability error that surveys have shown even doctors are prone to making.

Why you're probably ok:

The rarity of the disease far exceeds the error rate of the positive test. Meaning, the disease occurs in 1 out of a million people, so if you are tested at random and show positive, you only have a 1 out of 30,000 chance (the 3% false-positive rate) of being the the 1 person who truly has the disease.

marcos 126 points 8 months ago

The doctor is the one with the correct reaction there. Go do the second test.

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Windex007 86 points 8 months ago

I mean, yes...

But at 1/30,000 , they should say "get the second test... but be SUPER CAREFUL on the drive", since at 1/30000 you're still an order of magnitude more likely to die in an MVA.

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idiomaddict 22 points 8 months ago

This is ideal bedside manner.

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Windex007 22 points 8 months ago

I've always thought that I'd make an exceptional professional in the field of medicine.

The only thing really holding me back is my unfathomable depth of ignorance regarding the human body, or health in general.

At one point in my life, I believed that to be a deal breaker. Cheers, RFK Jr.

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SmackemWittadic 3 points 8 months ago

I think RFK can be convinced to believe that Windex has amazing health benefits, so this might be your chance!

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LodeMike 74 points 8 months ago

Accuracy and False Positive Rates are two different numbers.

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LifeInMultipleChoice 8 points 8 months ago

I'm tired and my brain is being dumb right now, but when you said that my first thought was of course American. 97% accuracy grouping bullets is a lot different than 97% sure a gun was fired.

One says Johnny got shot in the kidney, the other says a truck may have misfired down the road.

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RamRabbit 48 points 8 months ago

This is one of the main reasons doctors don't 'just give you a battery of tests'. Not only is that expensive, but if you are running dozens of tests, the chance one of them gives a false positive is pretty high. So now you not only wasted a pile of money, but you also think you have some rare disease you don't actually have. So you waste even more time and money treating that disease you don't have.

Doctors run tests for things they think you might actually have, which diminishes the false positive chance.

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themaninblack 2 points 7 months ago

I have been thinking about this for a while.

Would this actually diminish the false positive rate for the test? Would it just be more likely to get a true positive back?

Or maybe would the false negative result be less likely?

Does it depend on the sample group that was measured to get the accuracy statistics? If the sample group was random then does that actually make a difference?

Doing my head in

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Ryanmiller70 46 points 8 months ago

Tactical RPGs have basically taught me that anything below 100% is almost always a miss and even 100% isn't guaranteed.

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The_Picard_Maneuver 30 points 8 months ago

I missed a very important 96% shot in XCOM last night. I'm still thinking about it.

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rustydrd 30 points 8 months ago path: 0 22386721, hotness: undefined, score: 30, children: 0
RollingZeppelin 27 points 8 months ago

This is why we use specificity and sensitivity stats for medical tests. If the test has a sensitivity of 97%, you should definitely be worried.

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Zorcron 7 points 8 months ago

In the case of trying to minimize false positives, you want the specificity to be high, not necessarily the sensitivity, which is associated with false negatives.

And 97% specificity with a very low pretest probability still results in a low probability for disease, which is why screening for so many diseases is difficult, even if diagnosing them can be easy if there are clinical signs and symptoms in addition the the test. The clinical background can increase the pretest probability significantly, allowing the test to do its job.

A video about pretest probability from Dr. Rohin Francis whose YouTube videos are very informative in general.

Another very relevant video from 3Blue1Brown about the problem.

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RollingZeppelin 2 points 7 months ago

Yes, understood, ideally you would have two tests, one with high sensitivity to give some confidence that the disease is there, following by the high specificity test to compound the probability and rule out the false positive. Usually most tests have a trade off between specificity and sensitivity so two tests are needed.

Edit:
Watched the two videos, I love both these YouTubers but haven't seen either video before. The calculating of the Bayes factor as an update to the prior odds was very interesting, helped increase my understanding, thank you.

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over_clox 18 points 8 months ago

I almost died of a dental abscess back in 2008, which led to a multi systemic failure. That was fun, but I'm still alive today.

Fuckall with worrying about life anymore, if I ain't dead yet, well I'm not dead. I'm doing okay BTW..

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Mouselemming 11 points 8 months ago

Any day we're all breathing is a good day

Be well, friend

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Jarix 7 points 8 months ago

Today I broke my personal record for consecutive days lived!

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naticus 5 points 8 months ago

Whoa, congrats! I should check my high score too..... OMG would you believe it?! Me too!

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Jarix 3 points 8 months ago

Amazing I love it! Congrats friend!

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HeyThisIsntTheYMCA 2 points 8 months ago

I mean, fuck 2026 and all but I can have a good day if I have good food.

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toynbee 14 points 8 months ago

So you're telling me there's a chance

Interpret it how you will.

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somerandomperson1231 4 points 7 months ago

Alright since I am actually currently learning about Bayes theorem. Assuming 97% accuracy means 3% chance of false negative and false positive. If you test positive. You have a 0.0032% of actually having the disease. If someone wants to double check me I encourage it.

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Formfiller 1 point 8 months ago

Outlier?

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nightwatch_admin -2 points 8 months ago

That slop picture in the middle is uncalled for, I mean there are limits

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Bwaz -5 points 8 months ago

What statistician is this referring to? Certainly not one who understands probabilities. The first number has nothing to do with it. You tested positive, and there's only a 3% chance that result is wrong. Time to settle your affairs.

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drcobaltjedi 15 points 8 months ago

In a sample of 1 million people, 1 person will have the disease, 30,000 however will test positive for having the disease. Notice how the false positives count is way higher than the actual positive count.

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stephen01king 2 points 8 months ago

Is 97% accuracy rate the same as a 3% false positive rate? It might be a combination of false positive and false negative rate.

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Zorcron 5 points 8 months ago

Accuracy is defined in relation to a specific population or dataset with a specific rate of disease, not for any individual. To properly characterize the test, you need to know the specificity and sensitivity, and together they tell you how a test will perform on an individual and how much an individual’s pre-test probability increases in the case of a positive test or decreases based on a negative test.

Don’t worry if it’s confusing, Baysean statistics is often counter-intuitive.

If you're interested, here is a very good 3Blue1Brown video that explains the concept very well.

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stephen01king 3 points 8 months ago

Thank's for the link. Probability and statistics in general is not intuitive to me, not just for this type.

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Bwaz -1 points 8 months ago

How does that matter if I have a 97% chance of actually having the disease? A lot more people than I have won the lottery, doesn't have a thing to do with whether I will.

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drcobaltjedi 3 points 8 months ago

Its right 97% of the time. That does not mean you have a 97% chance of having the disease. The 3% error rate accounts for significantly more false positives than it accounts for false negatives on a disease that's 1 in a million. Again, with a 3% error rate, there will be 30000 false positive test results in a million. 30000 in a million is a larger number than 1 in a million.

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pnelego 1 point 7 months ago path: 0 22384715 22470776, hotness: undefined, score: 1, children: 0
ilinamorato 1 point 8 months ago

As far as I can see, you can't really fear or rejoice with the results until you know the false positive/negative ratio.

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