Stanford scientists regrow lost cartilage and reverse arthritis in major breakthrough

13 hours ago by VetOfTheSeas to c/upliftingnews

A new treatment that blocks an aging-related protein restored lost cartilage in old mice and helped prevent arthritis after knee injuries. Human cartilage samples showed similar signs of regeneration, raising hopes for a future drug that could repair joints instead of replacing them.
Eyekaytee 39 points 13 hours ago

man all the shit that works on mice

we must have made super jacked non-aging bio mice by now

seriously though hope this transfers, shitty joints just suck, no fun at all - signed an algae oil drinker

path: 0 24381501, hotness: undefined, score: 39, children: 3
chaogomu 18 points 11 hours ago

This drug has already gone through Phase 1 human trials for a separate condition.

Phase 1 trials only test safety in healthy adults, but this drug passed. (Still awaiting the paper on the trial)

The delivery method was a once a day pill.

path: 0 24381501 24382649, hotness: undefined, score: 18, children: 0
corsicanguppy 7 points 12 hours ago

Right? After a lifetime of walking, I'm gonna need some work soon -- feet, mainly. Please let this get to an applicable fix before it's too late!

path: 0 24381501 24381679, hotness: undefined, score: 7, children: 0
Danarchy 6 points 7 hours ago

Some of us already do bro.. just the other day I told off a fella “never speak to me or my super jacked non-aging bio mouse again”

path: 0 24381501 24386170, hotness: undefined, score: 6, children: 0
gravitas_deficiency 22 points 12 hours ago

Oh shit this is awesome. I’ve got some stuff that’s wrong with my knees, and this would be fantastic.

path: 0 24381917, hotness: undefined, score: 22, children: 1
Itsamelemmy 16 points 12 hours ago

My wife recently had her knee replaced. After seeing her recovery, hopefully this is available before I need mine done. Otherwise, it's gonna have to hurt like hell non stop before I consider getting mine done.

path: 0 24381917 24382169, hotness: undefined, score: 16, children: 0
saltesc 20 points 11 hours ago

I think a part of getting older is just watching medical science get better as the world gets shittier and realising the two cancel each other out so a natural death is still the preferred option. This is probably how people felt off the back of a world war, the depression, and then in the middle of another world war, someone's like,

"Check out penicillin! I accidentally discovered it like a decade ago."

"Nah, I'm good, thanks."

path: 0 24383195, hotness: undefined, score: 20, children: 1
Mycatiskai 8 points 6 hours ago

Yeah my dad was discussing MAID (medically assisted death) recently, he is in his late 70s.

He lost his heel in a motorcycle accident in the 1970s and they butchered up his right inner thing taking a chunk out and putting it on his foot. So now both his legs are in constant pain and he spends most of his day high as a kite to deal with the pain. He can barely walk anymore. He got through cancer a few years back which made matters worse and he lost his sense of taste so he gets to be in pain all day and not taste anything enjoyable.

Nothing medical is going to improve his life drastically so if MAID is what he wants then I will support him.

path: 0 24383195 24387163, hotness: undefined, score: 8, children: 0
antbricks 14 points 11 hours ago

Semaglutides and other weight loss drugs will hopefully make this treatment less needed in the future. I hope this somehow gets funding, testing, and approval before then to help all the folks with existing damage.

path: 0 24382478, hotness: undefined, score: 14, children: 7
Reverendender 4 points 9 hours ago

Too bad insurance in the US doesn't cover them for weight loss.

path: 0 24382478 24384749, hotness: undefined, score: 4, children: 1
ColeSloth 2 points 5 hours ago

It will in 2032 when the cheap stuff is allowed here.

path: 0 24382478 24384749 24388421, hotness: undefined, score: 2, children: 0
elucubra -7 points 9 hours ago

weight loss drugs? How about having a fucking decent diet. I mean, the whole "I need drugs to reach a healthy weight because I eat like shit" is really moronic.

path: 0 24382478 24384681, hotness: undefined, score: -7, children: 4
tetrachromacy 6 points 7 hours ago

This is a privileged viewpoint. Some people have problems losing weight because sugary foods are literally addicting(and in the US at least suffer is added to nearly everything). Some people experience what's called "food noise", in which their brain is constantly thinking about eating something, which can be a tremendous ongoing strain to block. Everyone is different, and just because some people can diet without going mad or breaking from the strain doesn't mean it should be that way for everyone.

Think about the weight loss drugs being less of an easy way to lose weight and more like it's addressing the mental and physical aspect of weight loss. If you've got food noise and an unhealthy relationship with food, then even if you're able to master your cravings, it takes an outsize amount of your concentration/spoons to handle. This can leave one deficient in other areas like maintaining their mental health, interpersonal relationships, hygiene, or any number of other things. It's not a moral or personal failing to need help, dieting or otherwise.

path: 0 24382478 24384681 24386608, hotness: undefined, score: 6, children: 1
halcyoncmdr 2 points an hour ago

And that doesn't even begin to touch the subject of food deserts. Many areas of the country, in the middle of dense cities, have absolutely no grocery stores for miles even if people want to be healthy and make food at home.

path: 0 24382478 24384681 24386608 24390878, hotness: undefined, score: 2, children: 0
khannie 4 points 7 hours ago

This is such a short sighted view. Humans are designed to eat more than they need for very good evolutionary reasons, we're just at the point now where you can do so for pennies. Obesity is on the rise everywhere as a result of this.

There are factors outside "just eat better bro" at play here. Carbs are incredibly cheap these days and eating healthily is comparatively expensive. There's a reason (several really) that obesity is higher among lower income folks. You couple that with "food desserts", ready meals and lack of free time and it's a terrible recipe.

I eat well myself and I consider myself lucky to be able to do so. Just a little of putting yourself in the shoes of someone else and not assuming laziness would do you the world of good.

path: 0 24382478 24384681 24386723, hotness: undefined, score: 4, children: 0
southsamurai 2 points 4 hours ago

Alas, saying that is so moronic that my irony detector exploded

path: 0 24382478 24384681 24389122, hotness: undefined, score: 2, children: 0
Reverendender 6 points 9 hours ago

There is hope for my hands and wrists, maybe!

path: 0 24384768, hotness: undefined, score: 6, children: 0
daannii 5 points 7 hours ago

Arthritis causes bone damage too. So. Idk how it's going to regrow bone joints by repairing cartilage but I'm not a medical doctor.

I realize bone can repair itself but there are limits.

path: 0 24386438, hotness: undefined, score: 5, children: 1
ripcord 5 points 3 hours ago

God damn no one here can let anything just be good

path: 0 24386438 24389785, hotness: undefined, score: 5, children: 0
Formfiller 2 points an hour ago

They need to redeem themselves because Stanford also gave us Peter Thiel

path: 0 24390768, hotness: undefined, score: 2, children: 0
psycotica0 1 point a few seconds ago

I've been sad lately, watching the creaky old mice shuffling around my yard, so it's nice that there's something coming down the pipe to help them regain mobility.

path: 0 24391451, hotness: undefined, score: 1, children: 0
upliftingnews
upliftingnews

@lemmy.world

login for more options
19193
1368
4742

Welcome to /c/UpliftingNews (rules), a dedicated space where optimism and positivity converge to bring you the most heartening and inspiring stories from around the world. We strive to curate and share content that lights up your day, invigorates your spirit, and inspires you to spread positivity in your own way. This is a sanctuary for those seeking a break from the incessant negativity and rage (e.g. schadenfreude) often found in today's news cycle. From acts of everyday kindness to large-scale philanthropic efforts, from individual achievements to community triumphs, we bring you news—in text form or otherwise—that gives hope, fosters empathy, and strengthens the belief in humanity's capacity for good, from a quality outlet that does not publish bad copies of copies of copies.

Here in /c/UpliftingNews, we uphold the values of respect, empathy, and inclusivity, fostering a supportive and vibrant community. We encourage you to share your positive news, comment, engage in uplifting conversations, and find solace in the goodness that exists around us. We are more than a news-sharing platform; we are a community built on the power of positivity and the collective desire for a more hopeful world. Remember, your small acts of kindness can be someone else's big ray of hope. Be part of the positivity revolution; share, uplift, inspire!

go to feed...